The Blades, who have gone three matches unbeaten under Bryan Robson will be without Nick Montgomery (broken foot) and is expected to sit out the remainder of the season.
blades v iron
Gary Speed should be passed fit to face the Iron whilst new loan striker David Coterill from Wigan Athletic will be included in the squad.
Meanwhile Scunthorpe United will be without Martin Paterson and Andy Butler whom are both suspended as the Iron plan to complete the double over United following their 3-2 victory at Glanford Park earlier in the season.
On loan striker Geoff Horsfield (from Sheffield United) will not be allowed to play against his current club but Jack Hobbs from Liverpool could start.