Cresswell, 34 has been absent from the starting line-up in the last two games after not been included in the defeat at Milton Keynes Dons (0-1) and coming off the substitutes bench in our home draw with Stevenage (2-2) due to a shoulder injury sustained against Leyton Orient on 14 April.
Being also without Ched Evans the Blades lost control of second spot and must win at Exeter and pray that rivals Sheffield Wednesday fail to be Wycombe at Hillsborough.
"I'll be speaking with the physios and seeing what we can do," Cresswell told sufc.co.uk. "I'm ready to be involved and contribute in any way I can. I'm not one to give up and no one else here is either."
Cresswell, who has suffered nose, wrist and shoulder injuries in recent weeks, added: "I'm ready to do whatever it takes. I needed some jabs on Friday and then another just before the game, but I'll do whatever I can for the team.
"We're disappointed [to drop out of the automatic promotion places], of course we are, but we've got to lift ourselves because you never know what can happen. Strange things can occur on the final day."