The Blades last game was against Stoke City at the Britannia Stadium, the Potters are in the bottom three and made winning very difficult as they where held to a 0-0 draw.
Stuart McCall and Nick Montgomery both missed the 0-0 draw through injury while Phil Jagielka and Peter Ndlovu took there place, and unless McCall is fit then it is likely that Neil Warnock will keep the same side that played on Saturday.
Possible Starting Line-Up: Paddy Kenny, John Curtis, Shaun Murphy, Robert Page, Robert Kozluk, Peter Ndlovu, Phil Jagielka, Michael Brown, Michael Tonge, Dean Windass, Steve Kabba.
The Seagulls got of to a bang last Saturday when a Paul Brooker goal against Nottingham Forest gave them a 1-0 victory at there Withdean Stadium.
Brighton have been boosted by the return of Robbie Pethick and Gary
Hart from injury and suspension respectively as they look to surprise high-flying Blades at Bramall Lane. Hart, who was in-form before the 4 game ban faces competition from Paul Brooker and Tony Rougier to partner Bobby Zamora up-front for the Seagulls.
Possible Starting Line-Up: Dave Beasant, Dean Blackwell, Danny Cullip, Paul Watson, Kerry Mayo, Simon Rodger, Richard Carpenter, Ivar Ingimarsson, Paul Brooker, Bobby Zamora, Tony Rougier.
Prediction: Sheffield United 2-1 Brighton & Hove Albion
Full Division One Fixtures (all Tuesday unless stated): Bradford City v Sheffield Wednesday, Burnley v Leicester City, Coventry City v Portsmouth (Wednesday), Crystal Palace v Wimbledon, Ipswich Town v Reading, Millwall v Norwich City, Nottingham Forest v Derby County (Wednesday), Preston North End v Walsall, Rotherham United v Grimsby Town, Sheffield United v Brighton & Hove Albion, Watford v Gillingham, Wolverhampton Wanderers v Stoke City.